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Understanding the Importance of Your White Blood Cell Count for Autoimmune Diseases

The Significance of Checking Your White Blood Cell Count

Your white blood cell count plays a crucial role in your immune system's functioning. Some individuals may have higher counts, while others have lower counts. The prevailing notion suggests that this range is normal for each person, but it may not always reflect optimal health. Unfortunately, many individuals go for extended periods with improper white blood cell counts without realizing the potential underlying issues.

Identifying Abnormal White Blood Cell Counts through Blood Work

To determine any potential causes of abnormal white blood cell counts, detailed blood work is essential. By examining blood samples, healthcare professionals can assess the precise count and identify any deviations from the optimal range. While most lab reports indicate a "normal" range of 4 to 11, the ideal range, often referred to as the "sweet spot," lies between 5 and 6.5. Even slight variations from this range can be indicative of underlying health conditions.

For instance, a reading of 7 suggests a mild condition that might be raising the white blood cell count. On the other hand, a reading of 4.5 may indicate a chronic infection weakening the immune system. It's important to note that white blood cell count comprises various categories, including neutrophils, lymphocytes, monocytes, eosinophils, and basophils, each serving distinct functions within the immune system.

Exploring the Different Types of White Blood Cells

Understanding the roles of different types of white blood cells can provide valuable insights into their significance in maintaining optimal health. Let's take a closer look at each category:

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Neutrophils combat and eliminate bacteria, as well as attack foreign debris in the body.


Lymphocytes fight against viruses and produce antibodies.


Monocytes play a vital role in cleaning up damaged cells. Their count significantly increases during mononucleosis (commonly known as "mono" or "the kissing disease").


Eosinophils are responsible for fighting parasites and cancer cells and are also involved in allergic reactions. Elevated levels of eosinophils often indicate the presence of a parasite.


Similar to eosinophils, basophils are primarily involved in allergic reactions.

High White Blood Cell Counts and their Implications

An abnormally high white blood cell count signifies an excessive number of white blood cells in the body. This can involve one or more individual types of white blood cells or even all of them. When the immune system is suppressed, it leads to lower levels of these cells, which puts individuals at greater risk for various diseases.

The Composition of Blood and the Importance of White Blood Cell Count

During blood tests, samples are spun in a machine to separate the different components. On average, red blood cells make up around 45% of the blood composition, while plasma, the fluid containing water, salts, minerals, and proteins, constitutes the remaining 55%. Notably, white blood cells account for merely 1% of the overall blood composition. Consequently, the white blood cell count plays a critical role in maintaining the body's immune response. Any imbalance, especially a low white blood cell count, can have significant negative consequences.

graph in test tube of the makeup of blood 55 percent plasma 45 percent red blood cells

These consequences include an increased risk of autoimmune diseases, autoimmune diseases themselves, an overactive immune system, or a weakened immune system.

The Link between White Blood Cell Dysregulation and Autoimmune Diseases

Individuals with autoimmune diseases often experience dysregulation in their white blood cell counts. Identifying the cause of this dysregulation is essential for effectively addressing their health conditions. Comprehensive testing, including advanced analysis of white blood cell counts and lymphocyte subcategories, can provide a clearer understanding of the dysregulation and guide appropriate treatment.

Advanced Testing for Precise Analysis of White Blood Cell Counts

In recent years, more advanced testing methods have emerged, enabling a more detailed breakdown of white blood cell counts. This testing also extends to lymphocyte subcategories, such as T cells, B cells, T-Helper (CD4) cells, and Cytotoxic (CD8) cells. By delving deeper into these levels, healthcare professionals can better comprehend any dysregulation and determine appropriate interventions.

cartoons left shows high white blood cell count right shows low white blood cell count

The Neglected Impact of Chronic Conditions on White Blood Cell Counts

Unfortunately, many individuals suffering from chronic conditions fail to investigate the underlying causes affecting their bodies. It is worth noting that patients with chronic conditions often display lower or low white blood cell counts. This emphasizes the importance of thorough investigation and tailored treatment to address their unique health needs.

low white blood cell count on patient labs dr. hugh wegwerth

Common Causes of White Blood Cell Dysregulation

Various factors can lead to abnormal white blood cell counts, either too high or too low. Some common causes include autoimmune diseases, low vitamin D levels, food and gluten sensitivities, pathogens, such as Lyme and mold, high insulin levels, hyperglycemia, hypoglycemia, stress, chronic inflammation, low hormone levels, low testosterone, yeast infections, Candida overgrowth, C. difficile, H. pylori, poor detoxification, chronic infections, leaky gut/brain, and dietary protein issues.

labs showing high and low white blood cell counts

The Need for Comprehensive Testing and Personalized Treatment

It is crucial to conduct comprehensive testing to identify the specific causes of white blood cell dysregulation. Unfortunately, the conventional healthcare system often fails to delve deeply into the underlying issues. As a practitioner, I prioritize thorough examination and collaborate closely with my patients to gather concrete data. By doing so, we can develop a guided path to wellness, providing hope for individuals struggling with their health.

Remember, there is always a light at the end of the tunnel, and with professional guidance and support, you can regain control over your health and well-being. I am here to help you on your journey towards optimal health, offering personalized care and empowering you to achieve lasting wellness.


[00:00:00] Hey, community, there's Dr Hugh Wegwerth [00:00:15] high white blood cell count or low [00:01:15] white blood cell count is 5.7 [00:02:00] potential low-grade mild infection [00:02:15] longstanding systemic infection [00:03:00] neutrophils, lymphocytes, monocytes, eosinophils, and basophils [00:04:00] neutrophils is really for bacteria [00:06:30] is your immune system [00:06:45] autoimmune disease or an increased immune system [00:09:00] high white blood cell count [00:09:45] here. They consider the normal range 3.4 to 10.8. [00:10:00] homeostasis immune system and that range is 5.0 to basically 6.5. [00:11:15] Here's another one. 9.8, This is lab high. [00:11:45] This person is 2.5. So that's really, really low. [00:12:30] We have 3.3. You can see the range in here. So 3.3, that's low [00:14:15] We have T cells, we have B cells, we have T helper cells. [00:14:30] We have cytotoxic, cytotoxic CD 8 cells. [00:14:45] different autoimmune diseases, diseases you could have a [00:15:00] suppressed immune system. [00:15:45] sweet spot, I like it to be 5.0 to 6.5 right here [00:17:00] You might have an autoimmune disease, you might have low vitamin D [00:17:15] might have food sensitivities [00:17:30] People have chronic conditions generally that are on the low side of white blood cell count. [00:17:45] mold, guess what happens. High insulin levels, hypoglycemia [00:18:00] pre-diabetic stress. chronic inflammation [00:18:15] low in DHEA or progesterone or testosterone or estrogen. [00:18:30] leaky gut, maybe have leaky brain


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